The 2013 Mercedes-Benz E350 4Matic is a relatively difficult vehicle to maintain when compared to other similar models. You will have to remove a large panel from under the vehicle in order to access the petcock. This will require you to contend with gravity to complete. Changing the headlight with reliability, as you will have to reach through the wheel well lining for access. This lining can grow tight to the vehicle and be difficult to peel back. The engine air filter is much more complicated to access than usual, as you will need to use additional tools to complete extra steps.
Some things are easier to repair on the 2013 Mercedes-Benz E350 4Matic. The components of the spare tire are easily accessible in the rear of the vehicle. This keeps the tire and jack kit ready to go in case of emergency. The engine coolant reservoir is easily visible in the engine bay. This will allow you to check and replenish the fluid level on a regular basis. Changing the daytime running bulb is no problem. You only have to reach behind the housing for access to the assembly.
If your brake fluid is a little low, learn how to add some here. Ignoring a low level leads to big problems2013 Mercedes-Benz E350 4Matic 3.5L V6 Sedan
Leaking coolant is usually a sign that your water pump needs to be replaced. This video shows you how to quickly plug it2013 Mercedes-Benz E350 4Matic 3.5L V6 Sedan
Low coolant levels is all to common - top yours up today2013 Mercedes-Benz E350 4Matic 3.5L V6 Sedan
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Coolant hoses wear out over time and need to be replaced - check 'em early and often2013 Mercedes-Benz E350 4Matic 3.5L V6 Sedan